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15 Responses to “Melanin Production”

1. Considering melanin is everywhere from your skin to your brain, and lack of neuromelanin is linked to several neurological disorders, including advanced Alzheimer’s, trying to stop it is probably a bad idea. Get your hair and skin bleached and buy some white contacts instead.

   SwampDonkey on October 15th, 2008 at 12:02 pm

2. Danger Will Robinson, Danger, Danger!

   You are thinking it would be cool to stop the melanin production in your skin, right? Well, it happens naturally in your body when all of the proper compounds are present (amino acids like cysteine, etc.) and all of your melanocytes are working properly.

   So you have a couple options… Stop the intake of those prerequisite compounds or stop your melanocytes from functioning properly. Deactivating all of your SKIN’s melanocytes would be a ridiculously invasive surgery and pretty much the equivalent of just skinning yourself…so lets not try that.

   The problem w/ ending your intake of those needed compounds is that they are used in other necessary processes that you don’t want to fuck around with and things like cysteine are non-essential so your body produces it whether you like it or not.

   BUT NONE OF THAT MATTERS!!
   —–On top of everything I have mentioned there is one extra little problem…melanin isn’t just in your skin…It’s in your eyes, inner ear, endocrine system, and your freaking brain stem.

   Do you still want to stop your body’s melanin production?
   Melanin deficiency is an aspect of numerous diseases and disorders… not something you want.

   Kent on October 15th, 2008 at 5:13 pm

3. Melanin and its relatives are involved in a large array of biological processes other than skin pigmentation… it’s current most relevant research area is in obesity of all things. I would recommend strongly against this, and I expect any specialists you find would feel the same way.

   There are drugs out there that might accomplish what you’re looking for, but they’ve not been tested on humans (or often even mammals) and are too early in development to even determine an appropriate dose, and the side effects and toxicity unpredictable. And unless you’re much better connected than you say you are, you haven’t got a hope of getting your hands on them anyway. Buying dermablend in bulk is as good as you’ll get without risking your life… maybe in 10 years time.

   redeye on October 15th, 2008 at 9:03 pm

4. One question…Are you insane!?

   Sade on October 16th, 2008 at 10:03 pm

5. Uh… What is Melanin?

   KittyDemon on October 17th, 2008 at 1:14 am

6. … Ask Michael Jackson.

   ba-ding-ch (drum/symbol joke noise)

   sorry.

   Lauren on October 17th, 2008 at 3:31 am

7. Unless you have Vitiligo, you shouldn’t be messing around with something like this.

   also, Michael Jackson had vitiligo…it’s a lot more obvious when you’re darker skinned, so he had shots to bleach the rest of the skin, so he didn’t look patchy. it’s also why he started wearing the white glove…vitiligo usually starts on the hands.

   christina on October 17th, 2008 at 10:01 am

8. I was going to say Michael Jackson too…Lauren beat me to it.

   He claimed he had vitiligo though, which does occur in some dark-skinned people. According to Wikipedia, best guess is that it’s an autoimmune disease that’s usually caused by a gene mutation. If you can figure out how to do that to yourself, you may not only get your desired look but a Nobel as well :eyeroll:

   Xenobiologista on October 17th, 2008 at 9:13 pm

9. Well, you’ve all been a help, and a laugh (Lauren). And I see how one might think I were crazy. I can’t describe the want of something such as this enough without sounding all whiny. I want my white hair. I want my red eyes, and I want my pale/white skin. I get people who look at me and just ask, “You want to be albino?” as if I’d suddenly reconsider, but all I can do is stare back at them blankly with a sincere “yes”. Then all I seem to get is a nervous laughter and them walking away…

   *Runs off to buy bleach and contacts*

   Maleficia on October 18th, 2008 at 1:59 am

10. I understand that, but be aware that albinism carries with it a series of ailments, some of which have been listed above by posters, most noticeably leading to a marked decrease in life expectancy. There is also blindness, in some cases. If it is the aesthetics you are after then yes, bleach and contacts are your best bet!

    Tiff Badhairdo on October 18th, 2008 at 7:44 am

11. Why does it matter that that person be aware of the downsides of albinism? It’s not like he/she would ever be able to acquire that genetic defect so going for the aesthetics is obviously the only option.

    Julius on October 18th, 2008 at 12:37 pm

12. Being aware of a condition that one aspires to have helps to understand what others who have that condition might actually have to deal with. Educating oneself is never a bad thing.

    Tiff Badhairdo on October 28th, 2008 at 9:12 am

13. Try Dr. Thienna

    kathy on March 5th, 2009 at 8:34 am

14. Use sub-lingual Glutahione, Pure L-Ascorbic acid and NAC cysteine. The combination should have a bleaching affect..

    Lumana on November 1st, 2009 at 10:16 am

15. Any bleaching achieved with the glutathione preparations that are becoming popular in South East Asia would be due to inhibition of melanin production, so the same risks as above would apply.

    That’s if it actually does anything. In a few minutes on google I’ve found the stuff marketed as tablets, creams, soaps and injectable ampules, pretty much everything short of crystals to freebase. The scientific literature does support that glutathione is involved in melanin production, but I wasn’t able to find anything confirming that high doses cause a skin bleaching effect.

    I call bunk, and if it’s somehow true then it’s likely very dangerous.

    redeye on November 4th, 2009 at 2:02 am

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